There is no desktop publishing software that can open the native MS Publisher. Other examples include Microsoft Access and Microsoft Visio both of which also aren’t available for Mac. It’s also worth bearing in mind that Microsoft doesn’t always release Mac versions of its Windows products.
Microsoft has never given an official reason why there is no version of Publisher for Mac but the most likely reason is because Mac users still represent a relatively small number of Microsoft product users. Why Is There No Microsoft Publisher For Mac? Microsoft has never released Publisher for Mac and there is no Mac version included in Office for Mac or Microsoft 365. The most recent version of Publisher is only available with a Microsoft 365 subscription but there is still a one off purchase desktop version of Publisher 2019 still available.
Microsoft Publisher is different from Microsoft Word because it focuses more on creative Desktop Publishing (DTP) than word processing software. Microsoft Publisher is a simple PC only desktop publishing application that focuses on page layout design.